DDF Berlin 2024: Global Drug Delivery & Formulation summit
The Global Drug Delivery and Formulation Summit is a leading event for professionals in the pharmaceutical industry specializing in drug delivery, formulation, and device development. The summit features over 100 scientific presentations, more than 90 industry experts as speakers, and includes four content streams spread over three days. The comprehensive agenda covers four key content streams: Small Molecules, Biologics, Technology & Innovation, and Device Development.
Poloxamer 188 variant for the formulation of biologics
Surfactants are used in the biopharmaceutical industry to stabilize antibodies in biologic formulations. In our research, a hydrophobic variant of Poloxamer 188 has shown promise in the formulation of biologics, particularly when used with primary packaging containing PDMS. We will share, that this formulation has been found to result in fewer visible particles of Protein-PDMS after prolonged storage compared to formulations with less hydrophobic P188. Additionally, the hydrophobic P188 has demonstrated a positive impact on antibody aggregation, with fewer larger aggregates detected after stress induction. These findings suggest that the use of hydrophobic P188 can improve the stability and quality of biologic formulations.
Join the presentation "Poloxamer 188 variant for the formulation of biologics" of our expert Nadine Löw on Thursday, May 23, 9:40am!